Tumour-derived small extracellular vesicles act as a barrier to therapeutic nanoparticle delivery

Nature Materials, Published online: 02 September 2024; doi:10.1038/s41563-024-01961-6

Cancer cell-derived small extracellular vesicles bind to therapeutic nanoparticles leading them from tumours to the liver for degradation. This mechanism is another barrier for the development of efficient nanoparticle-based cancer therapies.Nature Materials, Published online: 02 September 2024; doi:10.1038/s41563-024-01961-6Cancer cell-derived small extracellular vesicles bind to therapeutic nanoparticles leading them from tumours to the liver for degradation. This mechanism is another barrier for the development of efficient nanoparticle-based cancer therapies. Read More