An intelligent DNA nanodevice for precision thrombolysis

Nature Materials, Published online: 06 March 2024; doi:10.1038/s41563-024-01826-y

An intelligent DNA nanodevice, composed of DNA origami nanosheets and a thrombin-responsive DNA fastener, accurately delivers the appropriate dose of tissue plasminogen activator following activation by distinct thrombosis events.Nature Materials, Published online: 06 March 2024; doi:10.1038/s41563-024-01826-yAn intelligent DNA nanodevice, composed of DNA origami nanosheets and a thrombin-responsive DNA fastener, accurately delivers the appropriate dose of tissue plasminogen activator following activation by distinct thrombosis events. Read More