A DNA origami device spatially controls CD95 signalling to induce immune tolerance in rheumatoid arthritis

Nature Materials, Published online: 09 April 2024; doi:10.1038/s41563-024-01865-5

A pH-responsive DNA origami device displays a precise geometric array of CD95 ligands to selectively induce activated immune cell death and elicit localized immune tolerance to alleviate rheumatoid arthritis.Nature Materials, Published online: 09 April 2024; doi:10.1038/s41563-024-01865-5A pH-responsive DNA origami device displays a precise geometric array of CD95 ligands to selectively induce activated immune cell death and elicit localized immune tolerance to alleviate rheumatoid arthritis. Read More